The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis

SOX9 is a transcriptional activator required for chondrogenesis, and SOX5 and SOX6 are closely related DNA-binding proteins that critically enhance its function. We use here genome-wide approaches to gain novel insights into the full spectrum of the target genes and modes of action of this chondroge...

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Detalles Bibliográficos
Autores principales: Liu, Chia-Feng, Lefebvre, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787819/
https://www.ncbi.nlm.nih.gov/pubmed/26150426
http://dx.doi.org/10.1093/nar/gkv688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787819/
https://www.ncbi.nlm.nih.gov/pubmed/26150426
http://dx.doi.org/10.1093/nar/gkv688

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