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Dissecting the target specificity of RNase H recruiting oligonucleotides using massively parallel reporter analysis of short RNA motifs

Processing and post-transcriptional regulation of RNA often depend on binding of regulatory molecules to short motifs in RNA. The effects of such interactions are difficult to study, because most regulatory molecules recognize partially degenerate RNA motifs, embedded in a sequence context specific...

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Detalles Bibliográficos
Autores principales: Rukov, Jakob Lewin, Hagedorn, Peter H., Høy, Isabel Bro, Feng, Yanping, Lindow, Morten, Vinther, Jeppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787823/
https://www.ncbi.nlm.nih.gov/pubmed/26220183
http://dx.doi.org/10.1093/nar/gkv759