Paradoxical suppression of small RNA activity at high Hfq concentrations due to random-order binding

Small RNAs (sRNAs) are important regulators of gene expression during bacterial stress and pathogenesis. sRNAs act by forming duplexes with mRNAs to alter their translation and degradation. In some bacteria, duplex formation is mediated by the Hfq protein, which can bind the sRNA and mRNA in each pa...

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Detalles Bibliográficos
Autores principales: Sagawa, Shiori, Shin, Jung-Eun, Hussein, Razika, Lim, Han N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787825/
https://www.ncbi.nlm.nih.gov/pubmed/26261213
http://dx.doi.org/10.1093/nar/gkv777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787825/
https://www.ncbi.nlm.nih.gov/pubmed/26261213
http://dx.doi.org/10.1093/nar/gkv777

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