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Local sequence assembly reveals a high-resolution profile of somatic structural variations in 97 cancer genomes
Genomic structural variations (SVs) are pervasive in many types of cancers. Characterizing their underlying mechanisms and potential molecular consequences is crucial for understanding the basic biology of tumorigenesis. Here, we engineered a local assembly-based algorithm (laSV) that detects SVs wi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787836/ https://www.ncbi.nlm.nih.gov/pubmed/26283183 http://dx.doi.org/10.1093/nar/gkv831 |