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Collagen VI deficiency reduces muscle pathology, but does not improve muscle function, in the γ-sarcoglycan-null mouse

Muscular dystrophy is characterized by progressive skeletal muscle weakness and dystrophic muscle exhibits degeneration and regeneration of muscle cells, inflammation and fibrosis. Skeletal muscle fibrosis is an excessive deposition of components of the extracellular matrix including an accumulation...

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Detalles Bibliográficos
Autores principales: de Greef, Jessica C., Hamlyn, Rebecca, Jensen, Braden S., O'Campo Landa, Raul, Levy, Jennifer R., Kobuke, Kazuhiro, Campbell, Kevin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787905/
https://www.ncbi.nlm.nih.gov/pubmed/26908621
http://dx.doi.org/10.1093/hmg/ddw018