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Mutation and Human Exceptionalism: Our Future Genetic Load

Although the human germline mutation rate is higher than that in any other well-studied species, the rate is not exceptional once the effective genome size and effective population size are taken into consideration. Human somatic mutation rates are substantially elevated above those in the germline,...

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Detalles Bibliográficos
Autor principal: Lynch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788123/
https://www.ncbi.nlm.nih.gov/pubmed/26953265
http://dx.doi.org/10.1534/genetics.115.180471