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Inexpensive Computation of the Inverse of the Genomic Relationship Matrix in Populations with Small Effective Population Size

Many computations with SNP data including genomic evaluation, parameter estimation, and genome-wide association studies use an inverse of the genomic relationship matrix. The cost of a regular inversion is cubic and is prohibitively expensive for large matrices. Recent studies in cattle demonstrated...

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Detalles Bibliográficos
Autor principal: Misztal, Ignacy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788224/
https://www.ncbi.nlm.nih.gov/pubmed/26584903
http://dx.doi.org/10.1534/genetics.115.182089