A Gain-Of-Function Mutation in the Plcg2 Gene Protects Mice from Helicobacter felis-Induced Gastric MALT Lymphoma

Gastric mucosa-associated lymphoid tissue (MALT) lymphomas develop from a chronic Helicobacter infection. Phospholipase C gamma 2 (PLCG2) is important for B-cell survival and proliferation. We used BALB/c mice with a gain-of-function mutation in the Plcg2 gene (Ali5) to analyze its role in the devel...

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Detalles Bibliográficos
Autores principales: Gossmann, Jennifer, Stolte, Manfred, Lohoff, Michael, Yu, Philipp, Moll, Roland, Finkernagel, Florian, Garn, Holger, Brendel, Cornelia, Bittner, Alwina, Neubauer, Andreas, Huynh, Minh Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788355/
https://www.ncbi.nlm.nih.gov/pubmed/26966907
http://dx.doi.org/10.1371/journal.pone.0150411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788355/
https://www.ncbi.nlm.nih.gov/pubmed/26966907
http://dx.doi.org/10.1371/journal.pone.0150411

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