H3 Histone Tail Conformation within the Nucleosome and the Impact of K14 Acetylation Studied Using Enhanced Sampling Simulation

Acetylation of lysine residues in histone tails is associated with gene transcription. Because histone tails are structurally flexible and intrinsically disordered, it is difficult to experimentally determine the tail conformations and the impact of acetylation. In this work, we performed simulation...

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Detalles Bibliográficos
Autores principales: Ikebe, Jinzen, Sakuraba, Shun, Kono, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788430/
https://www.ncbi.nlm.nih.gov/pubmed/26967163
http://dx.doi.org/10.1371/journal.pcbi.1004788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788430/
https://www.ncbi.nlm.nih.gov/pubmed/26967163
http://dx.doi.org/10.1371/journal.pcbi.1004788

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