Generation and Characterization of a Human/Mouse Chimeric GD(2)-Mimicking Anti-Idiotype Antibody Ganglidiximab for Active Immunotherapy against Neuroblastoma

Vaccination with proteins mimicking GD(2) that is highly expressed on neuroblastoma (NB) cells is a promising strategy in treatment of NB, a pediatric malignancy with poor prognosis. We previously showed efficacy of ganglidiomab in vivo, a murine anti-idiotype (anti-Id) IgG1. In order to tailor immu...

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Detalles Bibliográficos
Autores principales: Eger, Christin, Siebert, Nikolai, Seidel, Diana, Zumpe, Maxi, Jüttner, Madlen, Brandt, Sven, Müller, Hans-Peter, Lode, Holger N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788445/
https://www.ncbi.nlm.nih.gov/pubmed/26967324
http://dx.doi.org/10.1371/journal.pone.0150479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788445/
https://www.ncbi.nlm.nih.gov/pubmed/26967324
http://dx.doi.org/10.1371/journal.pone.0150479

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