Morphine-Induced Preconditioning: Involvement of Protein Kinase A and Mitochondrial Permeability Transition Pore

BACKGROUND: Morphine induces myocardial preconditioning (M-PC) via activation of mitochondrial large conductance Ca(2+)-sensitive potassium (mK(Ca)) channels. An upstream regulator of mK(Ca) channels is protein kinase A (PKA). Furthermore, mK(Ca) channel activation regulates mitochondrial bioenerget...

Descripción completa

Detalles Bibliográficos
Autores principales: Dorsch, Marianne, Behmenburg, Friederike, Raible, Miriam, Blase, Dominic, Grievink, Hilbert, Hollmann, Markus W., Heinen, André, Huhn, Ragnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788451/
https://www.ncbi.nlm.nih.gov/pubmed/26968004
http://dx.doi.org/10.1371/journal.pone.0151025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788451/
https://www.ncbi.nlm.nih.gov/pubmed/26968004
http://dx.doi.org/10.1371/journal.pone.0151025

Ejemplares similares