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Morphine-Induced Preconditioning: Involvement of Protein Kinase A and Mitochondrial Permeability Transition Pore

BACKGROUND: Morphine induces myocardial preconditioning (M-PC) via activation of mitochondrial large conductance Ca(2+)-sensitive potassium (mK(Ca)) channels. An upstream regulator of mK(Ca) channels is protein kinase A (PKA). Furthermore, mK(Ca) channel activation regulates mitochondrial bioenerget...

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Detalles Bibliográficos
Autores principales:	Dorsch, Marianne, Behmenburg, Friederike, Raible, Miriam, Blase, Dominic, Grievink, Hilbert, Hollmann, Markus W., Heinen, André, Huhn, Ragnar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788451/ https://www.ncbi.nlm.nih.gov/pubmed/26968004 http://dx.doi.org/10.1371/journal.pone.0151025

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