Rb and p53 Liver Functions Are Essential for Xenobiotic Metabolism and Tumor Suppression

The tumor suppressors Retinoblastoma (Rb) and p53 are frequently inactivated in liver diseases, such as hepatocellular carcinomas (HCC) or infections with Hepatitis B or C viruses. Here, we discovered a novel role for Rb and p53 in xenobiotic metabolism, which represent a key function of the liver f...

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Detalles Bibliográficos
Autores principales: Nantasanti, Sathidpak, Toussaint, Mathilda J. M., Youssef, Sameh A., Tooten, Peter C. J., de Bruin, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788452/
https://www.ncbi.nlm.nih.gov/pubmed/26967735
http://dx.doi.org/10.1371/journal.pone.0150064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788452/
https://www.ncbi.nlm.nih.gov/pubmed/26967735
http://dx.doi.org/10.1371/journal.pone.0150064

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