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Blocking CXCL9 Decreases HIV-1 Replication and Enhances the Activity of Prophylactic Antiretrovirals in Human Cervical Tissues

OBJECTIVES: The interferon-gamma–induced chemokine CXCL9 is expressed in a wide range of inflammatory conditions including those affecting the female genital tract. CXCL9 promotes immune cell recruitment, activation, and proliferation. The role of CXCL9 in modulating HIV-1 infection of cervicovagina...

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Detalles Bibliográficos
Autores principales: Macura, Sherrill L., Lathrop, Melissa J., Gui, Jiang, Doncel, Gustavo F., Asin, Susana N., Rollenhagen, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788559/
https://www.ncbi.nlm.nih.gov/pubmed/26545124
http://dx.doi.org/10.1097/QAI.0000000000000891