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Mycobacterium leprae alters classical activation of human monocytes in vitro

BACKGROUND: Macrophages play a central role in the pathogenesis of leprosy, caused by Mycobacterium leprae. The polarized clinical presentations in leprosy are associated with differential immune activation. In tuberculoid leprosy, macrophages show a classical activation phenotype (M1), while macrop...

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Detalles Bibliográficos
Autores principales: Fallows, Dorothy, Peixoto, Blas, Kaplan, Gilla, Manca, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788835/
https://www.ncbi.nlm.nih.gov/pubmed/26973434
http://dx.doi.org/10.1186/s12950-016-0117-4