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Mycobacterium leprae alters classical activation of human monocytes in vitro
BACKGROUND: Macrophages play a central role in the pathogenesis of leprosy, caused by Mycobacterium leprae. The polarized clinical presentations in leprosy are associated with differential immune activation. In tuberculoid leprosy, macrophages show a classical activation phenotype (M1), while macrop...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788835/ https://www.ncbi.nlm.nih.gov/pubmed/26973434 http://dx.doi.org/10.1186/s12950-016-0117-4 |