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Estimation of genetic diversity in viral populations from next generation sequencing data with extremely deep coverage
BACKGROUND: In this paper we propose a method and discuss its computational implementation as an integrated tool for the analysis of viral genetic diversity on data generated by high-throughput sequencing. The main motivation for this work is to better understand the genetic diversity of viruses wit...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788855/ https://www.ncbi.nlm.nih.gov/pubmed/26973707 http://dx.doi.org/10.1186/s13015-016-0064-x |