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Estimation of genetic diversity in viral populations from next generation sequencing data with extremely deep coverage

BACKGROUND: In this paper we propose a method and discuss its computational implementation as an integrated tool for the analysis of viral genetic diversity on data generated by high-throughput sequencing. The main motivation for this work is to better understand the genetic diversity of viruses wit...

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Detalles Bibliográficos
Autores principales:	Zukurov, Jean P., do Nascimento-Brito, Sieberth, Volpini, Angela C., Oliveira, Guilherme C., Janini, Luiz Mario R., Antoneli, Fernando
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Software Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788855/ https://www.ncbi.nlm.nih.gov/pubmed/26973707 http://dx.doi.org/10.1186/s13015-016-0064-x

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