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Decreasing translation error rate in Escherichia coli increases protein function

BACKGROUND: Over-expressed native or recombinant proteins are commonly used for industrial and pharmaceutical purposes, as well as for research. Proteins of interest need to be purified in sufficient quantity, quality and specific activity to justify their commercial price and eventual medical use....

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Detalles Bibliográficos
Autores principales: Musa, Marina, Radman, Miroslav, Krisko, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788870/
https://www.ncbi.nlm.nih.gov/pubmed/26969280
http://dx.doi.org/10.1186/s12896-016-0259-8