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TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads

BACKGROUND: LILRA3 is an immunostimulatory molecule which can conditionally induce the proliferation of cytotoxic cells. LILRA3 has a deletion genotype which is associated with multiple immune disorders. In this study, we wanted to analyze the regulation of LILRA3 and its significance in the context...

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Detalles Bibliográficos
Autores principales: Low, Hui Zhi, Ahrenstorf, Gerrit, Pommerenke, Claudia, Habermann, Nadine, Schughart, Klaus, Ordóñez, David, Stripecke, Renata, Wilk, Esther, Witte, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788896/
https://www.ncbi.nlm.nih.gov/pubmed/26969150
http://dx.doi.org/10.1186/s12977-016-0248-y