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Intracerebroventricular administration of chondroitinase ABC reduces acute edema after traumatic brain injury in mice

BACKGROUND: Brain edema is a significant challenge facing clinicians managing severe traumatic brain injury (TBI) in the acute period. If edema reaches a critical point, it leads to runaway intracranial hypertension that, in turn, leads to severe morbidity or death if left untreated. Clinical data o...

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Detalles Bibliográficos
Autores principales: Finan, John D., Cho, Frances S., Kernie, Steven G., Morrison, Barclay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788921/
https://www.ncbi.nlm.nih.gov/pubmed/26969621
http://dx.doi.org/10.1186/s13104-016-1968-8