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Intracerebroventricular administration of chondroitinase ABC reduces acute edema after traumatic brain injury in mice
BACKGROUND: Brain edema is a significant challenge facing clinicians managing severe traumatic brain injury (TBI) in the acute period. If edema reaches a critical point, it leads to runaway intracranial hypertension that, in turn, leads to severe morbidity or death if left untreated. Clinical data o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788921/ https://www.ncbi.nlm.nih.gov/pubmed/26969621 http://dx.doi.org/10.1186/s13104-016-1968-8 |