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Mutational status of synchronous and metachronous tumor samples in patients with metastatic non-small-cell lung cancer

BACKGROUNDS: Despite reported discordance between the mutational status of primary lung cancers and their metastases, metastatic sites are rarely biopsied and targeted therapy is guided by genetic biomarkers detected in the primary tumor. This situation is mostly explained by the apparent stability...

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Detalles Bibliográficos
Autores principales: Quéré, Gilles, Descourt, Renaud, Robinet, Gilles, Autret, Sandrine, Raguenes, Odile, Fercot, Brigitte, Alemany, Pierre, Uguen, Arnaud, Férec, Claude, Quintin-Roué, Isabelle, Le Gac, Gérald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788951/
https://www.ncbi.nlm.nih.gov/pubmed/26968843
http://dx.doi.org/10.1186/s12885-016-2249-6