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Mutational status of synchronous and metachronous tumor samples in patients with metastatic non-small-cell lung cancer
BACKGROUNDS: Despite reported discordance between the mutational status of primary lung cancers and their metastases, metastatic sites are rarely biopsied and targeted therapy is guided by genetic biomarkers detected in the primary tumor. This situation is mostly explained by the apparent stability...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788951/ https://www.ncbi.nlm.nih.gov/pubmed/26968843 http://dx.doi.org/10.1186/s12885-016-2249-6 |