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Long genes and genes with multiple splice variants are enriched in pathways linked to cancer and other multigenic diseases
BACKGROUND: The role of random mutations and genetic errors in defining the etiology of cancer and other multigenic diseases has recently received much attention. With the view that complex genes should be particularly vulnerable to such events, here we explore the link between the simple properties...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788956/ https://www.ncbi.nlm.nih.gov/pubmed/26968808 http://dx.doi.org/10.1186/s12864-016-2582-9 |