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Human Genetics and the Causal Role of Lipoprotein(a) for Various Diseases
Lipoprotein(a) [Lp(a)] is a highly atherogenic lipoprotein that is under strong genetic control by the LPA gene locus. Genetic variants including a highly polymorphic copy number variation of the so called kringle IV repeats at this locus have a pronounced influence on Lp(a) concentrations. High con...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer US
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789197/ https://www.ncbi.nlm.nih.gov/pubmed/26896185 http://dx.doi.org/10.1007/s10557-016-6648-3 |