Validity of the MPTP-Treated Mouse as a Model for Parkinson’s Disease

Parkinson’s disease (PD) is characterized by dopaminergic (DA) neuron death in the substantia nigra (SN) and subsequent striatal adaptations. Mice treated with the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine (MPTP) are widely used as a model for PD. To assess the validity of the MPTP m...

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Detalles Bibliográficos
Autores principales: Klemann, Cornelius J. H. M., Martens, Gerard J. M., Poelmans, Geert, Visser, Jasper E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789200/
https://www.ncbi.nlm.nih.gov/pubmed/25676140
http://dx.doi.org/10.1007/s12035-015-9103-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789200/
https://www.ncbi.nlm.nih.gov/pubmed/25676140
http://dx.doi.org/10.1007/s12035-015-9103-8

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