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Adult Deletion of SRF Increases Epileptogenesis and Decreases Activity-Induced Gene Expression

Although the transcription factor serum response factor (SRF) has been suggested to play a role in activity-dependent gene expression and mediate plasticity-associated structural changes in the hippocampus, no unequivocal evidence has been provided for its role in brain pathology, such as epilepsy....

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Detalles Bibliográficos
Autores principales: Kuzniewska, Bozena, Nader, Karolina, Dabrowski, Michal, Kaczmarek, Leszek, Kalita, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789231/
https://www.ncbi.nlm.nih.gov/pubmed/25636686
http://dx.doi.org/10.1007/s12035-014-9089-7