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Comparative genomic analysis of toxin-negative strains of Clostridium difficile from humans and animals with symptoms of gastrointestinal disease

BACKGROUND: Clostridium difficile infections (CDI) are a significant health problem to humans and food animals. Clostridial toxins ToxA and ToxB encoded by genes tcdA and tcdB are located on a pathogenicity locus known as the PaLoc and are the major virulence factors of C. difficile. While toxin-neg...

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Detalles Bibliográficos
Autores principales: Roy Chowdhury, Piklu, DeMaere, Matthew, Chapman, Toni, Worden, Paul, Charles, Ian G., Darling, Aaron E., Djordjevic, Steven P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789261/
https://www.ncbi.nlm.nih.gov/pubmed/26971047
http://dx.doi.org/10.1186/s12866-016-0653-3