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TIRF imaging of Fc gamma receptor microclusters dynamics and signaling on macrophages during frustrated phagocytosis

BACKGROUND: Recent evidence indicates that in addition to the T-cell receptor, microclustering is an important mechanism for the activation of the B-cell receptor and the mast cell Fcε-receptor. In macrophages and neutrophils, particles opsonized with immunoglobulin G (IgG) antibodies activate the p...

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Detalles Bibliográficos
Autores principales: Lin, Jia, Kurilova, Svetlana, Scott, Brandon L., Bosworth, Elizabeth, Iverson, Bradley E., Bailey, Elizabeth M., Hoppe, Adam D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789268/
https://www.ncbi.nlm.nih.gov/pubmed/26970734
http://dx.doi.org/10.1186/s12865-016-0143-2