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5-Hydroxymethylcytosine discriminates between parathyroid adenoma and carcinoma

BACKGROUND: Primary hyperparathyroidism is characterized by enlarged parathyroid glands due to an adenoma (80–85 %) or multiglandular disease (~15 %) causing hypersecretion of parathyroid hormone (PTH) and generally hypercalcemia. Parathyroid cancer is rare (<1–5 %). The epigenetic mark 5-hydroxy...

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Detalles Bibliográficos
Autores principales: Barazeghi, Elham, Gill, Anthony J., Sidhu, Stan, Norlén, Olov, Dina, Roberto, Palazzo, F. Fausto, Hellman, Per, Stålberg, Peter, Westin, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789293/
https://www.ncbi.nlm.nih.gov/pubmed/26973719
http://dx.doi.org/10.1186/s13148-016-0197-2