Clinical relevance of the discrepancy in phenylalanine concentrations analyzed using tandem mass spectrometry compared with ion-exchange chromatography in phenylketonuria

INTRODUCTION: Metabolic control of phenylketonuria (PKU) and compliance with the low-phenylalanine (phe) diet are frequently assessed by measuring blood phe concentrations in dried blood spots (DBS) collected by patients instead of plasma phe concentrations. OBJECTIVE: Our objective was to investiga...

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Detalles Bibliográficos
Autores principales: Stroup, Bridget M., Held, Patrice K., Williams, Phillip, Clayton, Murray K., Murali, Sangita G., Rice, Gregory M., Ney, Denise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789345/
https://www.ncbi.nlm.nih.gov/pubmed/27014575
http://dx.doi.org/10.1016/j.ymgmr.2016.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789345/
https://www.ncbi.nlm.nih.gov/pubmed/27014575
http://dx.doi.org/10.1016/j.ymgmr.2016.01.001

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