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IL-1ra Secreted by ATP-Induced P2Y(2) Negatively Regulates MUC5AC Overproduction via PLCβ3 during Airway Inflammation

Mucus secretion is often uncontrolled in many airway inflammatory diseases of humans. Identifying the regulatory pathway(s) of mucus gene expression, mucus overproduction, and hypersecretion is important to alleviate airway inflammation in these diseases. However, the regulatory signaling pathway co...

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Detalles Bibliográficos
Autores principales: Jeong, Jee-Yeong, Kim, Jiwook, Kim, Bokyoum, Kim, Joowon, Shin, Yusom, Kim, Judeok, Ryu, Siejeong, Yang, Yu-Mi, Song, Kyoung Seob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789511/
https://www.ncbi.nlm.nih.gov/pubmed/27034593
http://dx.doi.org/10.1155/2016/7984853