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IL-1ra Secreted by ATP-Induced P2Y(2) Negatively Regulates MUC5AC Overproduction via PLCβ3 during Airway Inflammation
Mucus secretion is often uncontrolled in many airway inflammatory diseases of humans. Identifying the regulatory pathway(s) of mucus gene expression, mucus overproduction, and hypersecretion is important to alleviate airway inflammation in these diseases. However, the regulatory signaling pathway co...
Autores principales: | Jeong, Jee-Yeong, Kim, Jiwook, Kim, Bokyoum, Kim, Joowon, Shin, Yusom, Kim, Judeok, Ryu, Siejeong, Yang, Yu-Mi, Song, Kyoung Seob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789511/ https://www.ncbi.nlm.nih.gov/pubmed/27034593 http://dx.doi.org/10.1155/2016/7984853 |
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