Reversal of phenotypes of cellular senescence by pan-mTOR inhibition

Cellular senescence, a state of essentially irreversible proliferation arrest, serves as a potent tumour suppressor mechanism. However, accumulation of senescent cells with chronological age is likely to contribute to loss of tissue and organ function and organismal aging. A crucial biochemical modu...

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Detalles Bibliográficos
Autores principales: Walters, Hannah E., Deneka-Hannemann, Sylwia, Cox, Lynne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789579/
https://www.ncbi.nlm.nih.gov/pubmed/26851731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789579/
https://www.ncbi.nlm.nih.gov/pubmed/26851731

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