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Telomere shortening leads to earlier age of onset in ALS mice

Telomere shortening has been linked to a variety of neurodegenerative diseases. Recent evidence suggests that reduced telomerase expression results in shorter telomeres in leukocytes from sporadic patients with amyotrophic lateral sclerosis (ALS) compared with healthy controls. Here, we have charact...

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Detalles Bibliográficos
Autores principales: Linkus, Birgit, Wiesner, Diana, MeΔner, Martina, Karabatsiakis, Alexander, Scheffold, Annika, Rudolph, K. Lenhard, Thal, Dietmar R., Weishaupt, Jochen H., Ludolph, Albert C., Danzer, Karin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789589/
https://www.ncbi.nlm.nih.gov/pubmed/26978042