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Influence of cell physiological state on gene delivery to T lymphocytes by chimeric adenovirus Ad5F35

Adoptive transfer of genetically-modified T cells is a promising approach for treatment of both human malignancies and viral infections. Due to its ability to efficiently infect lymphocytes, the chimeric adenovirus Ad5F35 is potentially useful as an immunotherapeutic for the genetic modification of...

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Detalles Bibliográficos
Autores principales: Zhang, Wen-feng, Shao, Hong-wei, Wu, Feng-lin, Xie, Xin, Li, Zhu-Ming, Bo, Hua-Ben, Shen, Han, Wang, Teng, Huang, Shu-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789598/
https://www.ncbi.nlm.nih.gov/pubmed/26972139
http://dx.doi.org/10.1038/srep22688