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Influence of cell physiological state on gene delivery to T lymphocytes by chimeric adenovirus Ad5F35
Adoptive transfer of genetically-modified T cells is a promising approach for treatment of both human malignancies and viral infections. Due to its ability to efficiently infect lymphocytes, the chimeric adenovirus Ad5F35 is potentially useful as an immunotherapeutic for the genetic modification of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789598/ https://www.ncbi.nlm.nih.gov/pubmed/26972139 http://dx.doi.org/10.1038/srep22688 |