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FADD regulates NF-κB activation and promotes ubiquitination of cFLIP(L) to induce apoptosis
Tumor Necrosis Factor-α canonically induces the activation of NF-κB and associated gene product cellular FLICE-like inhibitory protein (cFLIP(L)) to promote cell survival. Previously, we demonstrated that ectopic expression of the Fas associated death domain (FADD) diminishes the expression of cFLIP...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789601/ https://www.ncbi.nlm.nih.gov/pubmed/26972597 http://dx.doi.org/10.1038/srep22787 |