Synchronized targeting of Notch and ERBB signaling suppresses melanoma tumor growth through inhibition of Notch1 and ERBB3

Despite significant advances in melanoma therapy, melanoma remains the deadliest form of skin cancer, with a five-year survival of only 15%. Novel treatments are therefore required to address this disease. Notch and ERBB are evolutionarily conserved signaling cascades required for the maintenance of...

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Detalles Bibliográficos
Autores principales: Zhang, Keman, Wong, Poki, Salvaggio, Christine, Salhi, Amel, Osman, Iman, Bedogni, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789778/
https://www.ncbi.nlm.nih.gov/pubmed/26967479
http://dx.doi.org/10.1016/j.jid.2015.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789778/
https://www.ncbi.nlm.nih.gov/pubmed/26967479
http://dx.doi.org/10.1016/j.jid.2015.11.006

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