Noggin4 is a long-range inhibitor of Wnt8 signalling that regulates head development in Xenopus laevis

Noggin4 is a Noggin family secreted protein whose molecular and physiological functions remain unknown. In this study, we demonstrate that in contrast to other Noggins, Xenopus laevis Noggin4 cannot antagonise BMP signalling; instead, it specifically binds to Wnt8 and inhibits the Wnt/β -catenin pat...

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Detalles Bibliográficos
Autores principales: Eroshkin, Fedor M., Nesterenko, Alexey M., Borodulin, Alexander V., Martynova, Natalia Yu., Ermakova, Galina V., Gyoeva, Fatima K., Orlov, Eugeny E., Belogurov, Alexey A., Lukyanov, Konstantin A., Bayramov, Andrey V., Zaraisky, Andrey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789793/
https://www.ncbi.nlm.nih.gov/pubmed/26973133
http://dx.doi.org/10.1038/srep23049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789793/
https://www.ncbi.nlm.nih.gov/pubmed/26973133
http://dx.doi.org/10.1038/srep23049

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