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Inverse regulation of two classic Hippo pathway target genes in Drosophila by the dimerization hub protein Ctp

The LC8 family of small ~8 kD proteins are highly conserved and interact with multiple protein partners in eukaryotic cells. LC8-binding modulates target protein activity, often through induced dimerization via LC8:LC8 homodimers. Although many LC8-interactors have roles in signaling cascades, LC8’s...

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Detalles Bibliográficos
Autores principales: Barron, Daniel A., Moberg, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789802/
https://www.ncbi.nlm.nih.gov/pubmed/26972460
http://dx.doi.org/10.1038/srep22726