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The regulatory element READ1 epistatically influences reading and language, with both deleterious and protective alleles

BACKGROUND: Reading disability (RD) and language impairment (LI) are heritable learning disabilities that obstruct acquisition and use of written and spoken language, respectively. We previously reported that two risk haplotypes, each in strong linkage disequilibrium (LD) with an allele of READ1, a...

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Detalles Bibliográficos
Autores principales: Powers, Natalie R, Eicher, John D, Miller, Laura L, Kong, Yong, Smith, Shelley D, Pennington, Bruce F, Willcutt, Erik G, Olson, Richard K, Ring, Susan M, Gruen, Jeffrey R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789805/
https://www.ncbi.nlm.nih.gov/pubmed/26660103
http://dx.doi.org/10.1136/jmedgenet-2015-103418