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MRI with hyperpolarised [1-(13)C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model

OBJECTIVES: Pancreatic cancer (PCa) is treatable by surgery when detected at an early stage. Non-invasive imaging methods able to detect both established tumours and their precursor lesions are needed to select patients for surgery. We investigated here whether pancreatic preneoplasia could be detec...

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Detalles Bibliográficos
Autores principales: Serrao, Eva M, Kettunen, Mikko I, Rodrigues, Tiago B, Dzien, Piotr, Wright, Alan J, Gopinathan, Aarthi, Gallagher, Ferdia A, Lewis, David Y, Frese, Kristopher K, Almeida, Jaime, Howat, William J, Tuveson, David A, Brindle, Kevin M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789827/
https://www.ncbi.nlm.nih.gov/pubmed/26347531
http://dx.doi.org/10.1136/gutjnl-2015-310114