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RGD(F/S/V)-Dex: towards the development of novel, effective, and safe glucocorticoids

Dexamethasone (Dex) is an effective glucocorticoid in treating inflammation and preventing rejection reaction. However, the side effects limit its clinical application. To improve its druggable profile, the conjugates of RGD-peptide-modified Dex were presented and their enhanced anti-inflammation ac...

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Detalles Bibliográficos
Autores principales: Jiang, Xueyun, Zhao, Ming, Wang, Yuji, Zhu, Haimei, Zhao, Shurui, Wu, Jianhui, Song, Yuanbo, Peng, Shiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789840/
https://www.ncbi.nlm.nih.gov/pubmed/27022245
http://dx.doi.org/10.2147/DDDT.S99568