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RGD(F/S/V)-Dex: towards the development of novel, effective, and safe glucocorticoids
Dexamethasone (Dex) is an effective glucocorticoid in treating inflammation and preventing rejection reaction. However, the side effects limit its clinical application. To improve its druggable profile, the conjugates of RGD-peptide-modified Dex were presented and their enhanced anti-inflammation ac...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789840/ https://www.ncbi.nlm.nih.gov/pubmed/27022245 http://dx.doi.org/10.2147/DDDT.S99568 |