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A Clinical Drug Library Screen Identifies Tosufloxacin as Being Highly Active against Staphylococcus aureus Persisters

To identify effective compounds that are active against Staphylococcus aureus (S. aureus) persisters, we screened a clinical drug library consisting of 1524 compounds and identified six drug candidates that had anti-persister activity: tosufloxacin, clinafloxacin, sarafloxacin, doxycycline, thiostre...

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Detalles Bibliográficos
Autores principales: Niu, Hongxia, Cui, Peng, Yee, Rebecca, Shi, Wanliang, Zhang, Shuo, Feng, Jie, Sullivan, David, Zhang, Wenhong, Zhu, Bingdong, Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790289/
https://www.ncbi.nlm.nih.gov/pubmed/27025627
http://dx.doi.org/10.3390/antibiotics4030329