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Utility of the Biosynthetic Folate Pathway for Targets in Antimicrobial Discovery
The need for new antimicrobials is great in face of a growing pool of resistant pathogenic organisms. This review will address the potential for antimicrobial therapy based on polypharmacological activities within the currently utilized bacterial biosynthetic folate pathway. The folate metabolic pat...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790348/ https://www.ncbi.nlm.nih.gov/pubmed/27025730 http://dx.doi.org/10.3390/antibiotics3010001 |