Synthesis, Antibacterial Evaluation and QSAR of α-Substituted-N(4)-Acetamides of Ciprofloxacin and Norfloxacin

Twenty six α-substituted N(4)-acetamide derivatives of ciprofloxacin (CIPRO) and norfloxacin (NOR) were synthesized and assayed for antibacterial activity against Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Bacillus subtilis. The derivatives were primarily more active against...

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Detalles Bibliográficos
Autores principales: Qandil, Amjad M., Al-Zoubi, Lorca O., Al-Bakri, Amal G., Amawi, Haneen A., Al-Balas, Qosay A., Alkatheri, Abdulmalik M., Albekairy, Abdulkareem M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790363/
https://www.ncbi.nlm.nih.gov/pubmed/27025747
http://dx.doi.org/10.3390/antibiotics3030244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790363/
https://www.ncbi.nlm.nih.gov/pubmed/27025747
http://dx.doi.org/10.3390/antibiotics3030244

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