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Ciprofloxacin Affects Host Cells by Suppressing Expression of the Endogenous Antimicrobial Peptides Cathelicidins and Beta-Defensin-3 in Colon Epithelia

Antibiotics exert several effects on host cells including regulation of immune components. Antimicrobial peptides (AMPs), e.g., cathelicidins and defensins display multiple functions in innate immunity. In colonic mucosa, cathelicidins are induced by butyrate, a bacterial fermentation product. Here,...

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Detalles Bibliográficos
Autores principales: Sarker, Protim, Mily, Akhirunnesa, Mamun, Abdullah Al, Jalal, Shah, Bergman, Peter, Raqib, Rubhana, Gudmundsson, Gudmundur H., Agerberth, Birgitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790365/
https://www.ncbi.nlm.nih.gov/pubmed/27025750
http://dx.doi.org/10.3390/antibiotics3030353