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Ancient Adaptive Evolution of the Primate Antiviral DNA-Editing Enzyme APOBEC3G

Host genomes have adopted several strategies to curb the proliferation of transposable elements and viruses. A recently discovered novel primate defense against retroviral infection involves a single-stranded DNA-editing enzyme, APOBEC3G, that causes hypermutation of HIV. The HIV-encoded virion infe...

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Detalles Bibliográficos
Autores principales: Sawyer, Sara L, Emerman, Michael, Malik, Harmit S
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC479043/
https://www.ncbi.nlm.nih.gov/pubmed/15269786
http://dx.doi.org/10.1371/journal.pbio.0020275