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Designing dose-finding studies with an active control for exponential families

Optimal design of dose-finding studies with an active control has only been considered in the literature for regression models with normally distributed errors and known variances, where the focus is on estimating the smallest dose that achieves the same treatment effect as the active control. This...

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Detalles Bibliográficos
Autores principales: Dette, H., Kettelhake, K., Bretz, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790467/
https://www.ncbi.nlm.nih.gov/pubmed/26989261
http://dx.doi.org/10.1093/biomet/asv041