AP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development

PURPOSE: The homeodomain transcription factor, PITX2, is at the apex of a genetic pathway required for corneal development, but the critical effector genes regulated by the PITX2 remain unknown. The purpose of this study was to discover and validate PITX2-dependent mechanisms required for specifying...

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Detalles Bibliográficos
Autores principales: Chen, Lisheng, Martino, Vanessa, Dombkowski, Alan, Williams, Trevor, West-Mays, Judith, Gage, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790471/
https://www.ncbi.nlm.nih.gov/pubmed/26968737
http://dx.doi.org/10.1167/iovs.15-18103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790471/
https://www.ncbi.nlm.nih.gov/pubmed/26968737
http://dx.doi.org/10.1167/iovs.15-18103

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